Product overview

Name Z-DQMD-FMK
Description Cell permeable caspase 3 specific inhibitor
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Biological Data

Biological description Cell permeable caspase 3 specific inhibitor. Attenuates β-catenin degradation but does not affect β-catenin and GSK-3β phosphorylation

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in DMSO (13.71mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone
Molecular Weight 685.72
Molecular Formula C29H40FN5O11S
PubChem identifier 644197
SMILES [H]N([C@@H](CC(=O)OC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)C(=O)OCC1=CC=CC=C1
InChiKey QFITYVNVMNJELE-TUFLPTIASA-N

References for Z-DQMD-FMK

References are publications that support the biological activity of the product
  • Photodynamic therapy in combination with talaporfin sodium induces mitochondrial apoptotic cell death accompanied with necrosis in glioma cells.

    Miki Y et al (2013) Biol Pharm Bull 36(2) : 215-21.
  • Inhibiting caspase-3 activity blocks beta-catenin degradation after focal ischemia in rat.

    Zhang H et al (2008) Neuroreport 19(8) : 821-4.

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