L-Glutamate

(HB0383)

Product overview

  • Name
    L-Glutamate
  • Short description
    Glutamate receptor excitatory neurotransmitter
  • Biological description
    Predominant excitatory neurotransmitter in the CNS. Active at ionotropic and metabotropic glutamate receptors. Physiological roles in vivo. Also associated with neuronal cell death and neurodegenerative disease pathogensesis.
  • Alternative names
    L-glutamic acid
  • Biological action
    Agonist
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    (S)-1-Aminopropane-1,3-dicarboxylic acid
  • Molecular Weight
    147.13
  • Chemical structure
    L-Glutamate  [56-86-0]
  • Molecular Formula
    C5H9NO4
  • CAS Number
    56-86-0
  • PubChem identifier
    33032
  • SMILES
    C(CC(=O)O)[C@@H](C(=O)O)N
  • InChi
    InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
  • InChiKey
    WHUUTDBJXJRKMK-VKHMYHEASA-N
  • MDL number
    MFCD00002634
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    Room temperature
  • Solubility overview
    Soluble in 0.1M NaOH (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for L-Glutamate

  • Ionotropic and metabotropic glutamate receptor structure and pharmacology.

    Kew JN et al (2005) Psychopharmacology (Berl) 179(1) : 4-29.
    PubMedID: 15731895
  • Modulation of gene expression of adenosine and metabotropic glutamate receptors in rat's neuronal cells exposed to L-glutamate and [60]fullerene.

    Giust D et al (2014) J Biomed Nanotechnol 10(8) : 1610-9.
    PubMedID: 25016660
  • Glutamate receptor-mediated inhibition of L-glutamate efflux from cerebral cortex in vitro.

    Hainsworth AH et al (2006) Brain Res 1114(1) : 36-40.
    PubMedID: 16904087