Novel tool for studying GPCR desensitization
An exclusive from Hello Bio, Cmpd101 is a novel, potent, selective G-protein coupled receptor kinase 2 and 3 inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). Selective over other kinases. Can be used to study roles of GRK2/3 in GPCR desensitization...Read more
AMPA receptors are members of the ionotropic class of glutamate receptors and consist of GluA1 (formerly GluR1), GluA2 (formerly GluR2), GluA3 (formerly GluR3) and GluA4 (formerly GluR4) subunits.They assemble as homomers or heteromers to form functional AMPA receptors. Researchers can save 50% on AMPA receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.