I made the discovery that the NMDA receptor is the trigger for the induction of LTP using D-AP5 synthesized by Jeff Watkins, the discoverer of the NMDA receptor... I now obtain my D-AP5 from Hello Bio. I love their products and ethos and that is why I accepted a position on their Scientific Advisory Board.Professor Graham Collingridge, winner of The Brain Prize, 2016
NMDA receptors (NMDARs) are voltage-dependent and ligand-gated ionotropic glutamate receptors that also require co-activation with glycine or D-serine. NMDA receptors are heterotetrameric and are comprised of GluN1, GluN2 (GluN2A, GluN2B, GluN2C, GluN2D), and GluN3 (GluN3A, GluN3B) subunits. Researchers can save 50% on NMDA receptor (NMDAR) agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio- they are up to half the price of other suppliers.