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(RS)-CPP

(HB0036)
Data

Product overview

  • Name
    (RS)-CPP
  • Short description
    Potent, selective, competitive NMDA receptor antagonist
  • Biological description
    Potent, selective and competitive NMDA receptor antagonist. Shows anticonvulsant activity.
  • Biological action
    Antagonist
  • Citations

Properties

  • Chemical name
    (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
  • Molecular Weight
    252.21
  • Chemical structure
    (RS)-CPP  [100828-16-8]
  • Molecular Formula
    C8H17N2O5P
  • CAS Number
    100828-16-8
  • PubChem identifier
    1228
  • SMILES
    C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O
  • InChi
    InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)
  • InChiKey
    CUVGUPIVTLGRGI-UHFFFAOYSA-N
  • MDL number
    MFCD00055136

Storing and Using Your Product

  • Storage instructions
    Room temperature (desiccate)
  • Solubility overview
    Soluble in water (100mM) and in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for (RS)-CPP

  • CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.

    Davies J et al (1986) Brain Res 382(1) : 169-73.
    PubMedID: 2876749
  • Action of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP): a new and highly potent antagonist of N-methyl-D-aspartate receptors in the hippocampus.

    Harris EW et al (1986) Brain Res 382(1) : 174-7.
    PubMedID: 2876750
  • CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.

    Lehmann J et al (1987) J Pharmacol Exp Ther 240(3) : 737-46.
    PubMedID: 2882014
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