Forskolin

(HB1348)

Product overview

  • Name
    Forskolin
  • Short description
    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer.
  • Biological description
    Cell permeable, reversible adenylyl cyclase activator. Increases cAMP levels and inhibits platelet-activating factor (PAF). Also inhibits mast cell degranulation and lowers intraocular pressure. Neuronal differentiation inducer. Displays vasodilating and hypotensive properties.
  • Biological action
    Activator
  • Customer comments

    I am currently working with forskolin. The quality of product and service is very satisfying. I am very happy to have access to your high quality products. Pojeong Park, PhD student, University of Bristol, UK

  • Our products in action

Images

Properties

  • Chemical name
    [3R-(3<α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
  • Molecular Weight
    410.51
  • Chemical structure
    Forskolin  [66575-29-9]
  • Molecular Formula
    C22H34O7
  • CAS Number
    66575-29-9
  • PubChem identifier
    47936
  • SMILES
    CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
  • InChi
    InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
  • InChiKey
    OHCQJHSOBUTRHG-KGGHGJDLSA-N
  • MDL number
    MFCD00082317

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    Soluble in DMSO (25 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Forskolin

  • Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling.

    Insel PA et al (2003) Cell Mol Neurobiol 23(3) : 305-14.
    PubMedID: 12825829
  • Forskolin and derivatives as tools for studying the role of cAMP.

    Alasbahi RH et al (2012) Pharmazie 67(1) : 5-13.
    PubMedID: 22393824
  • Forskolin: upcoming antiglaucoma molecule.

    Wagh VD et al (2012) J Postgrad Med 58(3) : 199-202.
    PubMedID: 23023353
  • Interactions of forskolin and adenylate cyclase. Effects on substrate kinetics and protection against inactivation by heat and N-ethylmaleimide.

    Awad JA et al (1983) J Biol Chem 258(5) : 2960-5.
    PubMedID: 6681815

Reviews

  • Verified customer, University of Bristol

    I am currently working with forskolin. The quality of product and service is very satisfying. I am very happy to have access to your high quality products.