Hello Bio Scientific Advisory Board member wins The Brain Prize – the ‘Nobel Prize for neuroscientists’
Professor Graham Collingridge, a member of Hello Bio’s Scientific Advisory Board has won The Brain Prize together with Professor Tim Bliss of University College London, and Professor Richard Morris from the University of Edinburgh. The Brain Prize is regarded as the equivalent of the Nobel Prize for neuroscientists.
Graham is a member of the Scientific Advisory Board for Hello Bio – a life science company that offers low cost research tools to scientists and neuroscientists worldwide. Professors Collingridge, Bliss and Morris studied a brain mechanism known as ‘Long-Term Potentiation’ (LTP), and showed that LTP is the basis for learning and memory. This has revolutionised scientists’ understanding of how memories are formed, retained and lost.
I made the discovery that the NMDA receptor is the trigger for the induction of LTP using D-AP5 synthesized by Jeff Watkins, the discoverer of the NMDA receptor. At that time it was not commercially available but Jeff kindly gave me a sample of his new antagonist. I now obtain my D-AP5 from Hello Bio. I love their products and ethos and that is why I accepted a position on their Scientific Advisory Board.
Professor Graham Collingridge, winner of The Brain Prize, 2016
We offer our heartfelt congratulations to Graham and Professors Bliss and Morris, for this amazing achievement. We are extremely proud to have Graham as part of the Hello Bio team – and privileged that he shares his expertise, ingenuity and enthusiasm with us.Graham has helped us to develop and offer a great range of low cost tools for neuroscientists, including many that are used to study learning and memory, such as D-AP5, NBQX and TTX. I am sure all of our customers will join me in congratulating Graham, together with Tim Bliss, and Richard Morris on this fantastic accomplishment
Steve Roome PhD, Managing Director and Founder, Hello Bio
Synaptic plasticity is the process by which synapses alter their efficiency and this property is used by the nervous system to store information. Synaptic plasticity is therefore crucial for the development of the nervous system, and for learning and memory.
Long-term potentiation (LTP) is a form of synaptic plasticity and Graham’s work has focused on synaptic plasticity in the hippocampus, a brain area important for learning and memory. His research has looked at the underlying mechanisms of different forms of LTP at these synapses using a combination of electrophysiological and imaging techniques. One of his notable achievements was discovering the role of the NMDA receptor in the induction of LTP. Find out more about Graham in the interview - Inside the brain of The Brain Prize winner
Research into this area is of great interest to scientists and clinicians as dysfunction of synaptic plasticity in the brain is thought to be involved in many disorders such Alzheimer's Disease, schizophrenia, Parkinson's disease, chronic stress, anxiety, depression, epilepsy and ischaemic brain injury.
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The Brain Prize
The Brain Prize is awarded annually by the Grete Lundbeck European Brain Research Foundation in Denmark and is worth one million Euros. It recognises scientists who have distinguished themselves by an outstanding contribution to neuroscience.
Hello Bio Scientific Advisory Board
Professor Graham Collingridge is a member of Hello Bio’s Scientific Advisory Board, joining a panel of eminent scientists and neuroscientists that also include Professor Min Zhuo, Professor David Jane, Professor Elek Molnar and Professor Kei Cho.
About Hello Bio
Hello Bio was founded by a team of experienced scientists and chemists who genuinely want to support life science research. Our aim is to offer a range of high quality life science tools at prices so low that as many researchers as possible will be able to afford them.
We offer a range of agonists, antagonists, inhibitors, activators, antibodies and fluorescent tools at up to half the price of other suppliers. The range includes:
We also offer a cost effective custom synthesis service for customers requiring specialist tools, or bulk quantities.