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Ligand-gated ion channel

Ligand-gated ion channels (also known as ionotropic receptors) are a group of transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

  1. 2-APB

    2-APB(HB1208)

    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Pack: Price: Qty:
    10mg
    $41
    50mg
    $136
  2. Description:

    5-HT4 receptor agonist and 5-HT3 antagonist

    Pack: Price: Qty:
    5mg
    $57
  3. Acamprosate calcium
    Description:

    GABA receptor agonist and glutamergic modulator

    Pack: Price: Qty:
    100mg
    $160
  4. ACBC

    ACBC(HB0100)

    Description:

    Competitive NMDA receptor partial agonist

    Pack: Price: Qty:
    1g
    $90
    5g
    $330
  5. Allopregnanolone
    Description:

    Potent GABAA receptor positive allosteric modulator

    Pack: Price: Qty:
    50mg
    $558
  6. α-Bungarotoxin(HB2038)

    Description:

    α7 subtype selective nAChR antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    1mg
    $140
  7. Amantadine hydrochloride
    Description:

    Non-competitive NMDA receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    1g
    $15
    5g
    $25
  8. AMPAR mediated whole cell current in response to S-AMPA

    (S)-AMPA(HB0052)

    Description:

    AMPA receptor agonist

    Purity :

    >99%

    Pack: Price: Qty:
    1mg
    $69
    5mg
    $97
    10mg
    $149
  9. AMPAR mediated whole cell current in response to RS-AMPA

    (R,S)-AMPA(HB0030)

    Description:

    Prototypic AMPA receptor agonist

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $104
    50mg
    $421
  10. Description:

    Potent nicotinic agonist

    Purity :

    >96%

    Pack: Price: Qty:
    1mg
    $136
  11. Aniracetam

    Aniracetam(HB0116)

    Description:

    Nootrophic AMPA receptor positive allosteric modulator

    Purity :

    >99%

    Pack: Price: Qty:
    100mg
    $218
    500mg
    $870
  12. DL-AP4

    DL-AP4(HB0249)

    Description:

    Broad spectrum glutamate antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $33
    1g
    $380
  13. D-AP5 inhibition of NMDA receptor mediated EPSCs

    D-AP5(HB0225)

    Reviews:
    Description:

    Selective, competitive NMDA receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    1mg
    $37
    10mg
    $82
    50mg
    $346
    100mg
    $476
    50mM (add 1ml water)
    $91
    100mM (add 1ml water)
    $164
  14. DL-AP5 inhibition of NMDA receptor mediated EPSCs

    DL-AP5(HB0251)

    Description:

    Competitive NMDA receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $41
    50mg
    $162
  15. DL-AP5 sodium inhibition of evoked NMDAR meditaed EPSCs
    Description:

    Competitive NMDA receptor antagonist. Sodium salt.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $54
    50mg
    $209
  16. Arcaine sulfate

    Arcaine sulfate(HB0118)

    Description:

    Competitive NMDA receptor antagonist / NOS inhibitor

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $75
  17. D-Aspartic acid

    D-Aspartic acid(HB0230)

    Description:

    NMDA receptor agonist

  18. L-Aspartic acid

    L-Aspartic acid(HB0374)

    Description:

    Endogenous NMDA receptor agonist

  19. (S)-ATPA(HB0854)

    Description:

    Selective GluK1 kainate / AMPA receptor agonist

    Pack: Price: Qty:
    5mg
    $160
  20. (+)-Bicuculline

    (+)-Bicuculline(HB0896)

    Description:

    Prototypic, competitive GABAA receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $107
  21. Bicuculline inhibition of GABAA receptor mediated IPSCs
    Reviews:
    Description:

    Prototypic, competitive GABAA receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $33
    50mg
    $109
    10mM (add 1ml water)
    $26
  22. Bicuculline methobromide inhibition of GABAA receptor IPSCs
    Description:

    Prototypic, competitive GABAA receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $89
    50mg
    $175
    125mg
    $354
  23. Bicuculline inhibition of GABAA receptor mediated IPSCs
    Reviews:
    Description:

    Prototypic, competitive GABAA receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $133
    50mg
    $228
    125mg
    $477
  24. Brilliant Blue G
    Description:

    Non-competitive P2X7 antagonist. Protein-binding dye.

  25. CFM-2

    CFM-2(HB0179)

    Description:

    Selective, non-competitive AMPA receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $552
  26. CIQ

    CIQ(HB0197)

    Reviews:
    Description:

    GluN2C / GluN2D subunit selective NMDA receptor positive allosteric modulator

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $122
  27. CNQX disodium inhibition of AMPA receptor mediated EPSCs
    Reviews:
    Description:

    Potent, competitive AMPA / kainate receptor antagonist. Disodium salt.

    Purity :

    >98%

    Pack: Price: Qty:
    1mg
    $36
    10mg
    $71
    50mg
    $299
    10mM (add 1ml water)
    $38
    20mM (add 1ml water)
    $65
  28. CNQX inhibition of AMPA receptor mediated EPSCs

    CNQX(HB0204)

    Description:

    Potent, competitive AMPA / kainate receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $45
    10mg
    $76
    25mg
    $214
    50mg
    $322
  29. CP 465022 hydrochloride
    Reviews:
    Description:

    Potent, non-competitive AMPA receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $457
    10mg
    $115
  30. (RS)-CPP

    (RS)-CPP(HB0036)

    Description:

    Potent, selective, competitive NMDA receptor antagonist

    Pack: Price: Qty:
    10mg
    $120
    50mg
    $484
  31. (R)-CPP

    (R)-CPP(HB0021)

    Reviews:
    Description:

    Potent NMDA receptor antagonist

    Pack: Price: Qty:
    1mg
    $50
    10mg
    $252
    50mg
    $1,009
  32. Cyclothiazide inhibition of AMPA receptor mediated EPSCs

    Cyclothiazide(HB0221)

    Description:

    AMPA receptor positive allosteric modulator. Inhibits AMPAR desensitization.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $43
    50mg
    $184
  33. Cytisine(HB2033)

    Description:

    Potent, selective neuronal nicotinic agonist

    Purity :

    >99%

    Pack: Price: Qty:
    25mg
    $178
  34. DNQX inhibition of AMPA receptor mediated EPSCs

    DNQX(HB0261)

    Reviews:
    Description:

    Selective, competitive AMPA / kainate receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $30
    50mg
    $98
  35. DNQX disodium inhibition of AMPA receptor mediated EPSCs
    Reviews:
    Description:

    Selective, competitive AMPA / kainate receptor antagonist. Sodium salt.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $38
    50mg
    $162
    10mM (add 1ml water)
    $26
    20mM (add 1ml water)
    $46
  36. Eliprodil

    Eliprodil(HB0274)

    Description:

    Non-competitive, GluN2B subunit selective NMDA receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $88
  37. Etomidate

    Etomidate(HB0937)

    Description:

    Potent GABAA receptor positive allosteric modulator

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $99
    50mg
    $390
  38. Evans blue

    Evans blue(HB0280)

    Description:

    Potent AMPA / kainate receptor antagonist. Vesicular L-glutamate uptake inhibitor.

  39. FGIN-1-27

    FGIN-1-27(HB0913)

    Description:

    Potent, selective MDR receptor agonist

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $103
  40. Flumazenil

    Flumazenil(HB0915)

    Description:

    GABAA receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    20mg
    $135
    100mg
    $538
  41. GABA

    GABA(HB0882)

    Description:

    Endogenous inhibitory neurotransmitter

  42. Gabapentin

    Gabapentin(HB0857)

    Description:

    Glutamate release inhibitor / VSCC modulator

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $29
    50mg
    $134
  43. Ganaxolone

    Ganaxolone(HB0938)

    Description:

    Potent GABAA receptor positive allosteric modulator

    Pack: Price: Qty:
    50mg
    $407
  44. Description:

    Phospho GluA1 (GluR1) subunit AMPA receptor rabbit polyclonal antibody (Ser845)

    Pack: Price: Qty:
    150μL
    $325
  45. Description:

    GluK2/GluK3 subunit kainate receptor rabbit polyclonal antibody

    Pack: Price: Qty:
    100μL
    $280
  46. Description:

    GluK5 subunit kainate receptor C-terminal domain specific rabbit polyclonal antibody

    Pack: Price: Qty:
    100μg
    $330
  47. Description:

    GluN1 subunit NMDA receptor mouse monoclonal antibody

    Pack: Price: Qty:
    50μg
    $199
  48. Description:

    GluN2A subunit NMDA receptor rabbit polyclonal antibody

    Pack: Price: Qty:
    100μL
    $285
  49. Description:

    GluN2B subunit NMDA receptor rabbit polyclonal antibody

    Pack: Price: Qty:
    10μg
    $330
  50. L-Glutamate

    L-Glutamate(HB0383)

    Description:

    Glutamate receptor excitatory neurotransmitter