G protein coupled receptors

G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. GPCRs include acetycholine muscarinic, adenosine, GABAB, and histamine receptors, and the metabotropic glutamate receptors (Group I, Group II and Group III). Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

  1. Description:

    Dihydrochloride salt of CNO - the prototypical DREADD activator

    Purity :

    >98%

    Clozapine N-oxide (CNO) dihydrochloride (water soluble)
    Pack: Price: Qty:
    5mg
    $45
    10mg
    $77
    25mg
    $167
    100mg
    $585
  2. Description:

    5-HT4 receptor agonist and 5-HT3 antagonist

    Pack: Price: Qty:
    5mg
    $57
  3. Description:

    Potent dopamine D4 receptor partial agonist

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $451
  4. Description:

    GABA receptor agonist and glutamergic modulator

    Acamprosate calcium
    Pack: Price: Qty:
    100mg
    $160
  5. Description:

    Serotonin N-acetyltransferase substrate

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $91
    50mg
    $332
  6. AdipoRon(HB3738)

    Description:

    Adiponectin receptor (AdipoR) agonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $267
  7. Description:

    AdipoR1 and AdipoR2 agonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $312
  8. AF-DX 116(HB1501)

    Description:

    Selective, competitive M2 receptor antagonist

    Purity :

    >98%

    AF-DX 116
    Pack: Price: Qty:
    10mg
    $185
    50mg
    $700
  9. Description:

    Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $71
  10. AM251(HB2776)

    Description:

    Potent, selective CB1 receptor antagonist / inverse agonist

    Purity :

    >98%

    Pack: Price: Qty:
    1mg
    $41
    10mg
    $87
    50mg
    $366
  11. Amauromine(HB3758)

    Description:

    Potent and selective CB1 receptor antagonist

    Purity :

    >95%

    Pack: Price: Qty:
    1mg
    $144
  12. Description:

    Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.

    AMD 3100 octahydrochloride
    Pack: Price: Qty:
    10mg
    $107
  13. Amisulpride(HB1879)

    Description:

    Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $93
  14. L-AP4(HB0370)

    Description:

    Selective group III mGluR agonist. Inhibits synaptic transmission.

    Purity :

    >99%

    L-AP4
    Pack: Price: Qty:
    5mg
    $56
    10mg
    $102
    25mg
    $227
    50mg
    $415
  15. (R)-Baclofen(HB0952)

    Description:

    Selective GABAB receptor agonist

    Purity :

    >99%

    Reversible inhibition of EPSC amplitude and increased EPSC paired pulse ration in response to Baclofen
    Pack: Price: Qty:
    10mg
    $44
    50mg
    $184
  16. Description:

    Selective GABAB receptor agonist

    Purity :

    >99%

    (RS)-Baclofen
    Pack: Price: Qty:
    1g
    $59
  17. BINA(HB0133)

    Reviews:
    Description:

    Potent, selective mGlu2 positive allosteric modulator

    Purity :

    >98%

    BINA
    Pack: Price: Qty:
    5mg
    $96
    10mg
    $142
    25mg
    $283
  18. Description:

    5-HT1A partial agonist

    Pack: Price: Qty:
    10mg
    $59
    50mg
    $216
  19. Description:

    Potent, selective endothelin receptor A (ETA) antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $361
  20. Description:

    Potent, selective endothelin B receptor (ETBR) antagonist

    Purity :

    >95%

    Pack: Price: Qty:
    500μg
    $152
    1mg
    $200
  21. Bradykinin(HB3101)

    Description:

    Endogenous bradykinin receptors agonist

    Purity :

    >95%

    Pack: Price: Qty:
    5mg
    $23
    25mg
    $91
  22. Description:

    Selective h5-HT1D antagonist

    Pack: Price: Qty:
    10mg
    $119
    50mg
    $451
  23. BRL 54443(HB1664)

    Description:

    Potent 5-ht1E/1F receptor agonist

    Pack: Price: Qty:
    10mg
    $103
    50mg
    $354
  24. Description:

    Classic 5-HT1A partial agonist

    Purity :

    >99%

    Pack: Price: Qty:
    100mg
    $54
  25. Description:

    Fluorescent adenosine receptor agonist

    CA200623 CellAura fluorescent adenosine agonist [NECA]
    Pack: Price: Qty:
    50μg
    $189
  26. Description:

    Competitive fluorescent adenosine receptor antagonist

    CA200634 CellAura fluorescent adenosine antagonist [XAC]
    Pack: Price: Qty:
    50μg
    $189
  27. Description:

    Fluorescent A3 adenosine receptor antagonist

    CA200645 CellAura fluorescent adenosine A3 antagonist [XAC]
    Pack: Price: Qty:
    50μg
    $189
  28. Description:

    Fluorescent β2 adrenoceptor antagonist

    CA200656 CellAura fluorescent β2 antagonist [(±)-propranolol]
    Pack: Price: Qty:
    50μg
    $189
  29. Description:

    Competitive fluorescent β2-adrenoceptor antagonist

    CA200689 CellAura fluorescent β2 antagonist [(S)-propranolol-red]
    Pack: Price: Qty:
    50μg
    $189
  30. Description:

    Fluorescent β2-adrenoceptor antagonist

    CA200693 CellAura fluorescent β2 antagonist [(S)-propranolol-green]
    Pack: Price: Qty:
    50μg
    $189
  31. Description:

    Fluorescent D1 dopamine receptor antagonist

    CA200773 CellAura fluorescent D1 antagonist [SKF83566-green]
    Pack: Price: Qty:
    50μg
    $189
  32. Description:

    Fluorescent H1 histamine receptor antagonist

    CA200799 CellAura fluorescent H1 antagonist [mepyramine]
    Pack: Price: Qty:
    50μg
    $189
  33. Description:

    Fluorescent H2 histamine receptor antagonist

    CA200821 CellAura fluorescent H2 antagonist [aminopotentidine]
    Pack: Price: Qty:
    50μg
    $189
  34. Description:

    Fluorescent H3 histamine receptor antagonist

    CA200843 CellAura fluorescent H3 antagonist [clobenpropit]
    Pack: Price: Qty:
    50μg
    $189
  35. Description:

    Fluorescent GABAB receptor antagonist

    Pack: Price: Qty:
    50μg
    $189
  36. Description:

    Fluorescent 5-HT1A receptor antagonist

    CA200992 CellAura fluorescent 5-HT1A antagonist [NAN-190]
    Pack: Price: Qty:
    50μg
    $189
  37. Description:

    Fluorescent 5-HT2A receptor antagonist

    Pack: Price: Qty:
    50μg
    $189
  38. Description:

    Fluorescent muscarinic M1 receptor antagonist

    Pack: Price: Qty:
    50μg
    $189
  39. Description:

    Fluorescent D3 antagonist [piperidinyl pyrazole-red]

    Pack: Price:
    50μg
    $189
    -
  40. Description:

    Fluorescent muscarinic M2 antagonist [benzylidine-red-2]

    Pack: Price: Qty:
    50μg
    $189
  41. Description:

    Fluorescent D3 antagonist [BP897-red]

    Pack: Price:
    50μg
    $189
    -
  42. Description:

    Fluorescent muscarinic M4 receptor antagonist

    Pack: Price: Qty:
    50μg
    $189
  43. Caffeine(HB2846)

    Description:

    Non-selective, competitive adenosine receptor antagonist / PDE inhibitor

    Caffeine
    Pack: Price: Qty:
    100mg
    $42
  44. Description:

    Nonpsychoactive cannabinoid found in cannabis

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $80
    50mg
    $300
  45. CDPPB(HB0175)

    Description:

    Selective mGlu5 positive allosteric modulator

    Purity :

    >98%

    CDPPB
    Pack: Price: Qty:
    10mg
    $122
    50mg
    $490
  46. CGP 35348(HB0955)

    Description:

    Selective GABAB receptor antagonist

    CGP 35348
    Pack: Price: Qty:
    10mg
    $138
  47. Description:

    Adenosine receptor agonist

    Purity :

    >99%

    2-Chloroadenosine (CADO)
    Pack: Price: Qty:
    250mg
    $283
    1g
    $725
  48. Description:

    Irreversible tryptophan hydroxylase inhibitor. Depletes 5-HT.

    Purity :

    >99%

    Pack: Price: Qty:
    100mg
    $54
  49. Description:

    Selective mGluR5 agonist. Water soluble sodium salt.

    Purity :

    >99%

    (R,S)-CHPG sodium salt
    Pack: Price: Qty:
    10mg
    $65
    50mg
    $269
  50. (R,S)-CHPG(HB0033)

    Description:

    Selective mGlu5 agonist

    Purity :

    >98%

    (R,S)-CHPG
    Pack: Price: Qty:
    10mg
    $59
    50mg
    $252